Rocuronium-induced neuromuscular block and sugammadex in pediatric patient with duchenne muscular dystrophy: A case Report
- Abstract
- Introduction: Anesthetic management of patients with Duchenne muscular dystrophy (DMD) is complicated because these
patients are more sensitive to nondepolarizing neuromuscular blocking agents (NMBAs) and are vulnerable to postoperative
complications, such as postoperative residual curarization and respiratory failure. Sugammadex is a new reversal agent for
aminosteroidal NMBAs, but its safety in children is controversial.
Clinical features: An 11-year-old boy with DMD underwent general anesthesia for a percutaneous nephrolithotomy. We used
rocuronium bromide and sugammadex to reverse the deep neuromuscular block. Reversal of neuromuscular block was done 15
minutes after administration of 2mg/kg of sugammadex. The patient’s recovery from anesthesia was uneventful, and he was
discharged to the postoperative recovery ward.
Conclusion: A delayed recovery was achieved, but no adverse events were observed, such as recurarization or hypersensitivity to
sugammadex. We report safe use of 2mg/kg of sugammadex to reverse a deep neuromuscular block in a child with DMD.
- All Author(s)
- J. E. Kim
; H. R. Chun
- Issued Date
- 2017
- Type
- Article
- Keyword
- duchenne muscular dystrophy; neuromuscular blocking agents; pediatrics; sugammadex
- Publisher
- Lippincott Williams & Wilkins
- ISSN
- 0025-7974
; 1536-5964
- Citation Title
- Medicine
- Citation Volume
- 96
- Citation Number
- 13
- Citation Start Page
- e6456
- Citation End Page
- e6456
- Language(ISO)
- eng
- DOI
- 10.1097/md.0000000000006456
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2446
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