Usefulness of noninvasive methods including assessment of liver stiffness by 2-dimensional shear wave elastography for predicting esophageal varices
- Abstract
- BACKGROUND: The aim of this study was to predict the presence of esophageal varices (EVs) by noninvasive tools combined with 2-dimensional shear wave elastography (2D-SWE), and to compare the diagnostic capabilities of 2D-SWE with those of transient elastography (TE). METHODS: Between January 2015 and December 2017, 289 patients with compensated advanced chronic liver disease (cACLD) who underwent consecutive 2D-SWE and EGD were enrolled. Capabilities for predicting the presence of EVs of 2D-SWE and models combining 2D-SWE with other noninvasive tools (modified LS-spleen-diameter-to-platelet-ratio score [mLSPS], platelet-spleen ratio score) were compared. A subgroup analysis was performed on 177 patients who also underwent simultaneous TE. RESULTS: The area under receiver operating characteristics (AUROCs) for detecting EVs for 2D-SWE alone vs. mLSPS, which included 2D-SWE, were 0.757 (95% confidence interval [CI], 0.701-0.810) and 0.813 (95% CI, 0.763-.857), respectively. The AUROCs for predicting varices needing treatment (VNT) for 2D-SWE and mLSPS were 0.712 (95% CI, 0.621-0.738) and 0.834 (95% CI, 0.785-0.875), respectively. For the 195 patients who underwent simultaneous TE and 2D-SWE, no differences in diagnostic performance were observed. CONCLUSIONS: The diagnostic performance of 2D-SWE is similar to that of TE for predicting the presence of EVs. The mLSPS, which includes 2D-SWE, seemed to be useful for predicting EVs.
- All Author(s)
- H. W. Yoo
; Y. S. Kim
; S. G. Kim
; J. J. Yoo
; S. W. Jeong
; J. Y. Jang
; S. H. Lee
; H. S. Kim
; Y. D. Kim
; G. J. Cheon
; B. Jun
; B. S. Kim
- Issued Date
- 2019
- Type
- Article
- Keyword
- 2D-SWE; Baveno VI; Esophageal varices; Real time shear wave elastography; Shear wave elastography; cACLD
- Publisher
- Associazione italiana per lo studio del fegato
- ISSN
- 1590-8658
; 1878-3562
- Citation Title
- Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
- Citation Volume
- 51
- Citation Number
- 12
- Citation Start Page
- 1706
- Citation End Page
- 1712
- Language(ISO)
- eng
- DOI
- 10.1016/j.dld.2019.06.007
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/877
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