Usefulness of magnifying endoscopy in post-endoscopic resection scar for early gastric neoplasm: a prospective short-term follow-up endoscopy study
- Abstract
- AIM: To investigate the relationship between post-endoscopic resection (ER) scars on magnifying endoscopy (ME) and the pathological diagnosis in order to validate the clinical significance of ME. METHODS: From January, 2007 to June, 2008, 124 patients with 129 post-ER scar lesions were enrolled. Mucosal pit patterns on ME were compared with conventional endoscopy (CE) findings and histological results obtained from targeted biopsies. RESULTS: CE findings showed nodular scars (53/129), erythematous scars (85/129), and ulcerative scars (4/129). The post-ER scars were classified into four pit patterns of sulci and ridges on ME: (I) 47 round; (II) 54 short rod or tubular; (III) 19 branched or gyrus-like; and (IV) 9 destroyed pits. Sensitivity and specificity were 88.9% and 62.5%, respectively, by the presence of nodularity on CE. Erythematous lesions were high sensitivity (100%), but specificity was as low as 36.7%. The range of the positive predictive value (PPV) on CE was as low as 10.6%-25%. Nine type IV pit patterns were diagnosed as tumor lesions, and 120 cases of type I-III pit patterns revealed non-neoplastic lesions. Thus, the sensitivity, specificity, and the PPV of ME were 100%. CONCLUSION: ME findings can detect the presence of tumor in post-ER scar lesions, and make evident the biopsy target site in short-term follow-up. Further large-scale and long-term studies are needed to determine whether ME can replace endoscopic biopsy.
- All Author(s)
- T. H. Lee
; I. K. Chung
; J. Y. Park
; C. K. Lee
; S. H. Lee
; H. S. Kim
; S. H. Park
; S. J. Kim
; H. D. Cho
; Y. Hwangbo
- Issued Date
- 2009
- Type
- Article
- Keyword
- Endoscopic mucosal resection; Endoscopic submucosal dissection; Magnifying endoscopy; Pit pattern; Scar
- Publisher
- Baishideng Publishing Group
- ISSN
- 1007-9327
; 2219-2840
- Citation Title
- World journal of gastroenterology
- Citation Volume
- 15
- Citation Number
- 3
- Citation Start Page
- 349
- Citation End Page
- 355
- Language(ISO)
- eng
- DOI
- 10.3748/wjg.15.349
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/872
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