난소의 경화성 간질종양 1예

Abstract

Sclerosing stromal tumor is a rare benign neoplasm of ovarian stromal origin, distinct from the thecoma-fibroma group and steroid (lipid) cell tumors clinically, pathologically, and radiographically. Unlike the thecoma-fibroma group of ovarian stromal tumors, which tend to occur in the fifth and sixth decades, the sclerosing stromal tumor predominantly affects young women with a mean age of 28 years. Microscopic examination reveals a heterogenous picture that is characterized by sclerosis, prominant vascularity and a disorganized admixture of fibroblasts and vacuolated cells. We could not demonstrate unequivocal hormonal activity in this case, although suggestive evidence for it has been reported in the literature in the form of clinical, histologic, electron microscopic and immunohistochemical findings. We recently experienced a case of sclerosing stromal tumor of the ovary in 20 year-old virgin woman. We report a case here with a brief review of the literature.