Prevalence and Characteristics of Restless Legs Syndrome in Korean Adults: A Study in Two Independent Samples of the General Population
- Abstract
- Background: Restless legs syndrome (RLS) is a common sleep disorder, although it has a low prevalence in Asian populations. However, the reported RLS prevalence in -Korean adults is mostly 4.5-12.1%, which is higher than that reported in other Asian populations. This study aimed to diagnose RLS and exclude mimicking conditions in 2 independent samples of Korean adults, and to compare its prevalence to that from previous studies performed in Asian countries.
Methods: Study populations included a (1) nationwide stratified random sample (n = 2,824; age 19-79 years) and (2) community-based cohort (n = 2,685; age 47-79 years). We applied the Cambridge-Hopkins diagnostic questionnaire to diagnose RLS and differentiate it from RLS mimics. Sleep-related symptoms, mood, and medical conditions were compared between the RLS and non-RLS groups. Prior studies of the RLS prevalence in Asia were systematically reviewed and compared to our findings.
Results: The adjusted RLS prevalence was 0.4 and 1.3% in populations 1 and 2, respectively. In both populations, subjects with RLS had more depression. The prevalence of RLS mimics was 5.1 and 2.6%, in populations 1 and 2, respectively. The RLS prevalence in Asia was higher when RLS was defined by the presence of essential clinical features and lower when a differential diagnosis was additionally implemented.
Conclusions: The RLS prevalence in Korean adults considering RLS mimics is comparable to that in adults from other Asian countries (< 2%). The reported RLS prevalence varies depending on the diagnostic method employed.
- All Author(s)
- T. J. Kim
; J. E. Yoon
; J. A. Park
; S. K. Lee
; M. K. Chu
; K. I. Yang
; W. J. Kim
; S. H. Park
; R. J. Thomas
; C. Shin
; C. H. Yun
- Issued Date
- 2019
- Type
- Article
- Keyword
- Cambridge-Hopkins diagnostic questionnaire; Epidemiology; Restless legs syndrome
- Publisher
- World Federation of Neurology Research Committee on Neuroepidemiology
- ISSN
- 0251-5350
; 1423-0208
- Citation Title
- Neuroepidemiology
- Citation Volume
- 52
- Citation Number
- 3-4
- Citation Start Page
- 193
- Citation End Page
- 204
- Language(ISO)
- eng
- DOI
- 10.1159/000496839
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2511
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