Risk of Advanced Colorectal Neoplasia According to the Number of High-Risk Findings at Index Colonoscopy: A Korean Association for the Study of Intestinal Disease (KASID) Study
- Abstract
- BACKGROUND: Data regarding outcomes for patients with multiple findings for high-risk adenomas are scarce. AIM: To compare the risk for colorectal neoplasm (CRN) recurrence according to the number of high-risk findings. METHODS: This was a retrospective and multicenter study. Patients who had one or more high-risk adenomas at the index colonoscopy and underwent follow-up colonoscopy 2.5 or more years after the index colonoscopy were included. The number of high-risk findings was defined as follows: number of adenomas larger than 1cm+number of adenomas with HGD+number of adenomas with a villous component+existence (counted as 1) or nonexistence (counted as 0) of three or more adenomas. RESULTS: A total of 1646 patients were included, and the mean duration between index and follow-up colonoscopy was approximately 4years. The cumulative incidence rate of recurrent advanced CRN in patients with three or more high-risk findings was higher than that in patients with one or two high-risk findings (p<0.001). However, the difference in 3-year cumulative incidence rates of recurrent advanced CRN between the two groups was not great, although it was statistically significant (4.8 vs. 2.3%, p=0.039). CONCLUSIONS: A 3-year surveillance interval for patients with multiple high-risk findings, regardless of the number of high-risk findings, appears reasonable.
- All Author(s)
- Y. S. Jung
; D. I. Park
; W. H. Kim
; C. S. Eun
; S. K. Park
; B. M. Ko
; G. S. Seo
; J. M. Cha
; J. J. Park
; K. O. Kim
; C. M. Moon
; Y. Jung
; E. S. Kim
; S. R. Jeon
; C. K. Lee
- Issued Date
- 2016
- Type
- Article
- Keyword
- Colonoscopy; High-risk adenoma; Colorectal neoplasia; Recurrence
- ISSN
- 0163-2116
- Citation Title
- Digestive Diseases and Sciences
- Citation Volume
- 61
- Citation Number
- 6
- Citation Start Page
- 1661
- Citation End Page
- 1668
- Language(ISO)
- eng
- DOI
- 10.1007/s10620-016-4038-0
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/2293
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