일개 제조 사업장 근로자들에서 직업성 소음노출과 혈중지질의 관련성

Abstract

Objective The study aimed to examine the relationship between occupational cumulative noise exposure and serum lipids as risk factor of ischemic heart disease. Methods Participants (n = 1,175) were workers of the steel product manufacturing factory exposed to more than 85 dB(A) of noise. We collected ambient noise and other materials monitoring data in workplace, laboratory test, and structured-questionnaires. Occupational noise exposure was defined as cumulative noise exposure calculated by duration of exposure and level of exposure. Serum lipids were total cholesterol, triglyceride, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and total cholesterol/HDL cholesterol. We examined the relationship between serum lipids and occupational noise exposure. Results In a noise exposure environment, 657 people (56.8%) worked for more than 10 years. Cumulative noise exposure increased significantly as exposure duration and noise level increased. Cumulative noise exposure were related to total cholesterol (P=0.001), LDL cholesterol (P=0.002), total cholesterol/HDL cholesterol (P=0.005) in correlation analysis. We conducted multiple linear regression analysis using the serum lipids and significant variables including cumulative noise exposure. We identified that total cholesterol was significantly related to cumulative noise exposure (β=0.072). Conclusion We propose occupational cumulative noise exposure may be significantly related to total cholesterol.