The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study
- Abstract
- Background: We estimated the nationwide burden of nosocomial S. aureus bloodstream infection (SA-BSI), a major cause of nosocomial infection, in South Korea. Methods: To evaluate the nationwide incidence of nosocomial SA-BSI, cases of SA-BSI were prospectively collected from 22 hospitals with over 500 beds over 4 months. Data on patient-days were obtained from a national health insurance database containing the claims data for all healthcare facilities in South Korea. The additional cost of SA-BSI was estimated through a matched case-control study. The economic burden was calculated from the sum of the medical costs, the costs of caregiving and loss of productivity. Results: Three hundred and thirty nine cases of nosocomial SA-BSI were included in the study: 254 cases of methicillin-resistant SA-BSI (MRSA-BSI) and 85 cases of methicillin-susceptible SA-BSI (MSSA-BSI). Death related to BSI occurred in 81 cases (31.9%) of MRSA-BSI and 12 cases (14.1%) of MSSA-BSI. The estimated incidence of nosocomial MRSA-BSI was 0.12/1,000 patient-days and that of nosocomial MSSA-BSI, 0.04/1,000 patient-days. The estimated annual cases of nosocomial BSI were 2,946 for MRSA and 986 for MSSA in South Korea. The additional economic burden per case of nosocomial SA-BSI was US $20,494 for MRSA-BSI and $6,914 for MSSA-BSI. Total additional annual cost of nosocomial SA-BSI was $67,192,559. Conclusion: In view of the burden of nosocomial SA-BSI, a national strategy for reducing nosocomial SA-BSI is urgently needed in South Korea.
- All Author(s)
- C. J. Kim
; H. B. Kim
; M. D. Oh
; Y. Kim
; A. Kim
; S. H. Oh
; K. H. Song
; E. S. Kim
; Y. K. Cho
; Y. H. Choi
; J. Park
; B. N. Kim
; N. J. Kim
; K. H. Kim
; E. J. Lee
; J. B. Jun
; Y. K. Kim
; S. M. Kiem
; H. J. Choi
; E. J. Choo
; K. M. Sohn
; S. Lee
; H. H. Chang
; J. H. Bang
; S. J. Lee
; J. H. Lee
; S. Y. Park
; M. H. Jeon
; N. R. Yun
; K. S. Grp
; G. Korea Infect Dis Study
- Issued Date
- 2014
- Type
- Article
- Keyword
- Staphylococcus aureus; Bacteremia; Incidence; Hospital infections
- ISSN
- 1471-2334
- Citation Title
- BMC infectious diseases
- Citation Volume
- 14
- Citation Number
- 590
- Citation Start Page
- 1
- Citation End Page
- 1
- Language(ISO)
- eng
- DOI
- 10.1186/s12879-014-0590-4
- URI
- http://schca-ir.schmc.ac.kr/handle/2022.oak/1062
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